Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives

Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives

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The isatin derivatives, ej10 Schiff bases, were synthesized by the reaction of isatin and various substituted primary amines and characterized by several spectroscopic methods.Investigation of the antimicrobial activity of the synthesized compounds was performed by the agar dilution method, against different strains of bacteria and one fungi.The antioxidative activity of the synthesized compounds was persol 3195 also determined.Some of the compounds have shown the significant activity against the selected strains of microorganisms and the antioxidative activity.[Projekat Ministarstva nauke Republike Srbije, br.

172013 i III 46010].